NEOVA Crème de la Copper, a luxe day cream with DNA repair enzymes and Copper Peptide Complex, in a jar with a reflective cap set against a minimalist white backdrop.

NEOVA Crème de la Copper on a clear acrylic block. The top-down macro view shows off the thick, white consistency of this hydrating facial repair cream.

NEOVA Crème de la Copper as step three of a four-step clinical skin care routine. The diagram shows: 1. Cleanse with a clear sparkling gel, 2. Treat with a yellow-tinted translucent serum, 3. Moisturize with a light lavender-grey cream, 4. Protect with a lightweight white sun protection lotion.

NEOVA Crème de la Copper educational image showing clinical before and after results with 'Overall improvement in fine lines & wrinkles after 8 weeks' on a light background.

Best Seller

Crème de la Copper

$140.00

Luxe Day Cream with DNA Repair Enzymes + Copper Peptide Complex® | 1.7 oz.

(4.9)

DNA CoFactor

Dry Skin

Loss of Firmness

Moisturizer

Powered by DNA CoFactor technology (copper peptides and DNA repair enzymes), NEOVA Crème de la Copper delivers deep hydration while supporting skin renewal. It helps improve the appearance of fine lines, firmness, and overall skin vitality throughout the day. With continued use, skin appears smoother, more resilient, and visibly rejuvenated.

What it's formulated to do

• Delivers steady doses of moisture to rehabilitate skin throughout the day.
• Provides powerful nourishing agents that help to organize mature skin into a dramatically improved moisture state and create a stronger protective barrier.
• Helps retain elasticity and firmness and visibly smooth uneven skin tones.

TEXTURE

Rich emollient cream with rapid absorption.

KEY INGREDIENTS

Copper Peptide Complex® (Bis [Tripeptide-1] Copper Acetate, GHK-Cu): A proprietary delivery system that uses the body’s natural protective carrier to deliver copper peptides, an essential micronutrient for skin health and strength, deep within the epidermis; essential for tissue repair and the stabilization of skin proteins.
Mitosomes (Arabidopsis Thaliana Extract): The liposome-encapsulated DNA repair enzyme extracted from a tiny mustard plant; recognizes the most common form of DNA oxidative damage and initiates its removal process to protect the energy center of the cell. Clinical studies show Mitosomes eliminate 90% of damage in 2 hours.
Ceramides: Lipids that support skin's barrier function, maintain moisture balance, and protect against irritating environmental aggressors.

ALL INGREDIENTS

Water (Aqua), Caprylic/Capric Triglyceride, Glyceryl Stearate, Propylene Glycol, Dimethicone, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Peg-100 Stearate, Palmitic Acid, Stearic Acid, Cetyl Alcohol, Polysorbate 20, Bis (Tripeptide-1) Copper Acetate, Arabidopsis Thaliana Extract, Lecithin, Vitis Vinifera(Grape) Seed Extract, Ceramide Eop, Ethylhexylglycerin, Hexylene Glycol, Allantoin, Ceramide Np, Ceramide Ap, Xanthan Gum, Sodium Lauroyl Lactylate, Glycerin, Magnesium Aluminum Silicate, Caprylyl Glycol, Aminomethyl Propanol, Glyceryl Behenate, Sodium Citrate, Sorbitan Sesquioleate, Polysorbate 60, Phytosphingosine, Cholesterol, Carbomer, Phenoxyethanol.

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NEOVA® is committed to ongoing innovation and compliance. As formulas are refined, ingredient lists shown on this website may differ from product packaging. Please refer to your product packaging for the most current ingredient information.

APPLICATION

Apply as a daytime moisturizer after cleansing and the appropriate serum. Follow with sunscreen every day.

Crème de la Copper

$140.00

KEY BENEFITS

DEEP HYDRATION

Delivers lasting moisture

BARRIER STRENGTHENING

Reinforces skin protection

ELASTICITY SUPPORT

Improves firmness + appearance

SKIN SMOOTHING

Refines texture and tone

HOW TO USE Crème de la Copper

1. Apply Crème de la Copper to clean skin once or twice daily.
2. Use after serum application.
3. Massage into face and neck until absorbed.
4. Use in the morning under SPF or at night.
5. Apply consistently for best results.

NEOVA Creme de la Copper – application: Close-up of cheek showing copper peptide cream being applied to support skin repair, improve elasticity, and reduce visible signs of aging.

Before

After

SEE THE RESULTS

REDUCTION IN FINE LINES AND WRINKLES IN 8 WEEKS

Crème de la Copper helps soften the appearance of fine lines and wrinkles, supporting smoother, firmer-looking skin.

Slide to compare real before and after results.

Protocol: DNA Total Repair & Crème de la Copper

STEP 1: CLEANSE

Gently purify your skin.

Microfoliant Cleanser

$46.00

★★★★★

4.9

STEP 2: TREAT

Target visible concerns.

DNA Total Repair

$125.00

★★★★★

4.7

STEP 3: MOISTURIZE

Support your skin's barrier.

Daily Moisture

$120.00

★★★★★

4.9

STEP 4: PROTECT

Defend daily against UVs.

Everyday

$62.00

★★★★★

4.9

FAQs About Crème de la Copper

Can I use only one moisturizer for both day and night instead of using Crème de la Copper and Night Therapy?

You can, but they’re designed to work best as a pair. Daytime formulas like Crème de la Copper focus on protecting against environmental stress, while Night Therapy supports overnight repair when skin is most receptive. Using both helps cover protection and recovery for more complete results.

Is it alright to use Crème de la Copper with retinol or retinoid skincare products?

Yes, copper peptide moisturizers can be paired with retinoid products. If you’re using a strong retinol, alternating or layering over it can help reduce irritation while still supporting skin repair.

Can NEOVA's Crème de la Copper be layered with vitamin C serums or exfoliating acids?

This day cream can be used in the same routine as vitamin C (like ascorbic acid) or alpha hydroxy acids, but some people prefer separating them (AM vs. PM) to minimize sensitivity and optimize performance of each active.

How do I update my subscription?

To update your subscription, you’ll need to access your account.
If you already have an account, simply sign in. If you don’t remember your password, you can reset it from the login page. Once logged in, click on “Manage Subscription” (located in the top left), then select “See More Details.” From there, you’ll be able to make changes such as ordering now, skipping or rescheduling an order, updating your shipping address or payment information, or adding products to your subscription.
If you don’t have an account yet, you’ll need to activate one first using the email sent to you. After activation, follow the same steps above to manage and update your subscription.

Fast Shipping

Orders ship within two business days. Rates are calculated at checkout.

30-Day returns

Unopened, unused items may be returned within 30 days of purchase for a refund.

Customer service

Our team is available Monday through Friday 9AM-5PM ET to assist.

Crème de la Copper