NEOVA Dual Matrix, a serum with retinol and DNA repair enzymes, in a white cylindrical bottle. The front label categorizes it under a purple "Correction" banner. The bottle features a brushed silver cap and contains 1.0 fl. oz. (30 ml). It is shown from a slightly low angle, standing on a white surface against a clean, bright minimalist background.

NEOVA Dual Matrix serum on a clear acrylic square. The top-down macro view of the serum shows it has a smooth, semi-opaque, pale yellow or cream-colored appearance with a slightly glossy finish. The composition is centered and brightly lit against a white background, showcasing the formula's lightweight, gel-like consistency.

Dual Matrix

$125.00

Regenerating Serum with DNA Repair Enzymes + Retinol | 1.0 oz.

(4.9)

Retinol

Lines and Wrinkles

Hyperpigmentation

Serum

Combining retinol with DNA repair technology, this dual-action treatment targets both skin renewal and repair in one formula. NEOVA Dual Metrix helps improve texture, tone, and visible signs of aging while supporting skin resilience. With consistent use, skin appears smoother, firmer, and more refined.

What it's formulated to do

• Targets and exfoliates visible trouble spots caused by photoaging and hormonally induced acne.
• Reduces the visible signs of photodamage and other known environmental damage with DNA repair enzymes.

TEXTURE

Rich serum with smooth consistency absorbs quickly.

CLINICAL STUDY

50% reduction in skin texture
41% reduction in skin surface scaling

Complete Clinical Study

KEY INGREDIENTS

Hydroxypinacolone Retinoate (HPR): a retinoic acid that is able to penetrate the deeper layers of the skin, initiating change at the cellular level, to combat the appearance of fine lines and wrinkles, increase skin elasticity, smooth skin texture and improve skin clarity, without irritating the skin.
Endosomes (Micrococcus Lysate): The liposome-encapsulated DNA repair enzyme UV-endonuclease, derived from the marine microorganism Micrococcus Lysate; this UV-resistant DNA Repair Enzyme helps improve the appearance of sun-damaged skin.

ALL INGREDIENTS

Water (Aqua), Caprylic/Capric Triglyceride, Cyclopentasiloxane, Coco-Caprylate, Polyglyceryl-10 Dipalmitate, Glycerin, Propylene Glycol, Stearyl Alcohol, Behenyl Alcohol, Butyrospermum Parkii Butter, Polymethylsilsesquioxane, Arachidyl Alcohol, Micrococcus Lysate, Hydroxypinacolone Retinoate, Squalane, Dimethyl Isosorbide, Arachidyl Glucoside, Sodium Stearoyl Lactylate, Carbomer, Xanthan Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Phytic Acid, Sodium Hydroxide, Ethylhexylglycerin, Polysorbate 60, Lecithin.

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NEOVA® is committed to ongoing innovation and compliance. As formulas are refined, ingredient lists shown on this website may differ from product packaging. Please refer to your product packaging for the most current ingredient information.

APPLICATION

Apply immediately after cleansing in the a.m. and p.m. daily. Follow with moisturizer, in addition to SPF protection after morning application.

Dual Matrix

$125.00

KEY BENEFITS

RETINOL RENEWAL

Boosts skin turnover

DNA SUPPORT

Targets visible photodamage

TEXTURE REFINEMENT

Smooths uneven surface

SPOT CLARITY

Improves visible trouble spots

HOW TO USE Dual Matrix

1. Apply immediately after cleansing.
2. Smooth a thin, even layer over face and neck.
3. Use morning and evening daily as tolerated.
4. Follow with moisturizer.
5. Apply SPF after morning use.

NEOVA Dual Matrix – application: Close-up of cheek showing anti-aging treatment being applied to improve skin firmness, reduce fine lines, and support collagen production.

STEP 1: CLEANSE

Gently purify your skin.

Microfoliant Cleanser

$46.00

★★★★★

4.9

STEP 2: TREAT

Target visible concerns.

Advanced HA

$130.00

★★★★★

4.8

STEP 3: MOISTURIZE

Support your skin's barrier

Clear Relief

$105.00

★★★★★

5.0

STEP 4: PROTECT

Defend daily against UVs.

Everyday

$62.00

★★★★★

4.9

FAQs About Dual Matrix

Does Dual Matrix combine retinol and DNA repair enzyme skincare technology?

Yes, NEOVA's Dual Matrix is a dual-active formula that combines retinoid with DNA repair enzymes in one product. This allows it to support both skin renewal and repair in a single step.

Can NEOVA's Dual Matrix [Retinol + DNA] be used with vitamin C or exfoliating acid skincare products?

Retinol-based combination skincare, like Dual Matrix, may be used with vitamin C or exfoliating acids, though alternating actives is often recommended in advanced skincare routines. This helps reduce the risk of irritation when layering multiple active ingredients.

What is combination retinol skincare and how does it differ from single-ingredient retinol products?

Combination retinol skincare refers to formulas that pair retinol with other active ingredients like peptides or DNA repair enzymes to support multi-target anti-aging skincare. Unlike single-ingredient retinol products, these formulations are designed to work across multiple pathways within a single skincare routine.

Can retinol and DNA repair enzyme skincare be used in the same nighttime routine?

Yes, many modern formulations are designed to safely combine these technologies. When properly formulated, they can complement each other by supporting both skin renewal and recovery overnight.

Fast shipping

Orders ship within two business days. Rates are calculated at checkout.

30-Day returns

Unopened, unused items may be returned within 30 days of purchase for a refund.

Customer service

Our team is available Monday through Friday 9AM-5PM ET to assist.

Dual Matrix

Dual Matrix

KEY BENEFITS

RETINOL RENEWAL

DNA SUPPORT

TEXTURE REFINEMENT

SPOT CLARITY

HOW TO USE Dual Matrix

Complete Your Regimen

STEP 1: CLEANSE

Microfoliant Cleanser

STEP 2: TREAT

Advanced HA

STEP 3: MOISTURIZE

Clear Relief

STEP 4: PROTECT

Everyday

FAQs About Dual Matrix