NEOVA Ultimate Redness Relief in a white jar. The front label identifies it as a "Repairing Complex DNA Repair Enzymes + Copper Peptide Complex®" and features a dark purple "Sensitive Relief" banner. The jar stands upright with a brushed silver screwcap, set against a clean, bright minimalist background.

NEOVA Ultimate Redness Relief on a clear acrylic square. The top-down macro view shows the product is a smooth, opaque cream with a distinct pale seafoam-green tint designed to neutralize redness. It has a rich, velvety consistency and is centered against a textured white background with soft, clean lighting.

NEOVA Ultimate Redness Relief as step three of a four-step clinical skin care routine. The diagram shows: 1. Cleanse with a clear cleanser gel, 2. Treat with a cream-yellow balm, 3. Moisturize with a light lavender-grey hydrating cream, 4. Protect with an SPF with a tint.

NEOVA Ultimate Redness Relief educational image showing clinical before and after results and overall improvement in redness in just 6 weeks, on a gray background.

Best Seller

Ultimate Redness Relief

$115.00

Repairing Complex with DNA Repair Enzymes + Copper Peptide Complex® | 1.7 oz.

(4.8)

DNA CoFactor

Redness

Sensitive Skin

Moisturizer

Ultimate Redness Relief is a targeted treatment designed to calm, hydrate, and visibly reduce persistent redness. Formulated with DNA CoFactor (copper peptides and DNA repair enzymes) and soothing hydrators, it helps strengthen the skin barrier while minimizing irritation. With consistent use, it promotes a more balanced, even-toned complexion.

What it's formulated to do

.Calm and hydrate persistent or reactive redness conditions. Gentle enough for skin prone to rosacea.

TEXTURE

Medium-dense cream with rapid absorption.

CLINICAL STUDY

In a 12-week study of patients with rosacea, 70% of study subjects showed significant improvement, with 50% going from mild to almost gone in 12 weeks.

Complete Clinical Study

PATENT

U.S. Patent No.: 7,179,789 B2

KEY INGREDIENTS

Copper Peptide Complex® (Bis [Tripeptide-1] Copper Acetate, GHK-Cu): A proprietary delivery system that uses the body’s natural protective carrier to deliver copper peptides, an essential micronutrient for skin health and strength, deep within the epidermis; essential for tissue repair and the stabilization of skin proteins.
Endosomes (Micrococcus Lysate): The liposome-encapsulated DNA repair enzyme UV-endonuclease, derived from the marine microorganism Micrococcus Lysate; this UV-resistant DNA Repair Enzyme helps improve the appearance of sun-damaged skin.
Sodium Hyaluronate: A salt form of hyaluronic acid; powerful humectant that deeply hydrates and holds up to 1,000 times its own weight in moisture, providing immediate hydration while improving the appearance of dry and dehydrated skin.

ALL INGREDIENTS

Water (Aqua), Cetyl Alcohol, Sodium Stearoyl Lactylate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Cyclopentasiloxane, Octyldodecyl Neopentanoate, Peg-100 Stearate, Palmitic Acid, Dimethicone, Stearic Acid, Ethylhexyl Stearate, Propylene Glycol Isoceteth-3 Acetate, Bis (Tripeptide-1) Copper Acetate, Micrococcus Lysate, Sodium Carboxymethyl Beta-Glucan, Sodium Hyaluronate, Ceramide Eop, Hydroxyethylcellulose, Squalane, Tocopheryl Acetate, Ceramide Np, Ceramide Ap, Phytosphingosine, Camellia Sinensis (Green Tea) Leaf Extract, Vitis Vinifera Seed Extract, Lecithin Phenoxyethanol, Sodium Lauroyl Lactylate, Capryl Glycol, Ethylhexylglycerin, Hexylene Glycol, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Glycerin, Cholesterol, Xanthan Gum, Carbomer.

--
NEOVA® is committed to ongoing innovation and compliance. As formulas are refined, ingredient lists shown on this website may differ from product packaging. Please refer to your product packaging for the most current ingredient information.

APPLICATION

Apply immediately after cleansing and after serum application as daily moisturizer. Follow with SPF protection after morning application.

Ultimate Redness Relief

$115.00

KEY BENEFITS

REDNESS RELIEF

Calms visible flushing

SENSITIVE SUPPORT

Comforts reactive skin

HYDRATION BOOST

Replenishes dry skin

BARRIER REPAIR

Strengthens skin resilience

HOW TO USE Ultimate Redness Relief

1. Apply immediately after cleansing
2. Use after serum application
3. Smooth evenly over face and areas prone to redness
4. Use as a daily moisturizer
5. Follow with SPF after morning application

NEOVA Ultimate Redness Relief – application: Close-up of cheek showing soothing treatment being applied to calm visible redness, reduce irritation, and support sensitive skin.

Before

After

SEE THE RESULTS

REDUCTION IN REDNESS IN 6 WEEKS

Ultimate Redness Relief helps calm visible redness and supports a more even, balanced-looking complexion over time.

Slide to compare real before and after results.

Protocol: Ultimate Redness Relief

STEP 1: CLEANSE

Gently purify your skin.

Cu3 Gentle Cleanser

$49.00

★★★★★

5.0

STEP 2: TREAT

Target visible concerns.

DNA Total Repair

$125.00

★★★★★

4.7

STEP 3: MOISTURIZE

Support your skin's barrier

Crème de la Copper

$140.00

★★★★★

4.9

STEP 4: PROTECT

Defend daily against UVs.

Silc Sheer 2.0

$69.00

★★★★★

4.9

FAQs About Ultimate Redness Relief

Does Ultimate Redness Relief from NEOVA contain DNA repair enzymes and copper peptide skincare ingredients?

NEOVA's Ultimate Redness Relief is formulated with DNA repair enzymes and copper peptide technology within a redness-focused clinical skincare system.

Is NEOVA's Ultimate Redness Relief designed for redness-prone and reactive skin skincare routines?

Ultimate Redness Relief is formulated specifically for reactive or redness-prone skin. It helps support barrier balance and improve overall skin comfort.

What is redness-targeted skincare?

Redness-targeted skincare focuses on calming appearance concerns associated with visible inflammation, skin sensitivity, and skin conditions, like rosacea, within clinical formulations.

Can Ultimate Redness Relief be used with Metronidazole cream?

Yes, apply Metronidazole first, then wait about 5 minutes before applying Ultimate Redness Relief. This helps ensure proper absorption while adding hydration and comfort to red or rosacea-prone skin.

Fast Shipping

Orders ship within two business days. Rates are calculated at checkout.

30-Day returns

Unopened, unused items may be returned within 30 days of purchase for a refund.

Customer service

Our team is available Monday through Friday 9AM-5PM ET to assist.

Ultimate Redness Relief