Day and Night Skincare. The Scientific Difference is Massive

It’s true. The biggest difference isn’t just about what you use. It’s when you do. Skin is under the influence of the Circadian Rhythm, our 24-hour internal clock, a biological cycle that steers skin functions. Everything from cell renewal to hydration levels to inflammation to how well products work.


Circadian Rhythms are a timekeeping system of sorts within the skin that allows it to anticipate changes that are associated with the cells’ day and night activity.
The science of the circadian cycle isn’t new, but the development of skin chronobiology has caught the eye of researchers, turning to the skin as a model system because of its constant interface with the outside world and natural light, the main timekeeping cue for the circadian system.

As shown in the 2023 study, Identification of key circadian rhythm genes in skin aging based on bioinformatics, “…a normal circadian rhythm can restore skin health by releasing cell repair hormones to repair damaged DNA, thereby reducing or even eliminating damage from aging-causing factors such as UV rays. Pathological mechanisms of skin aging, such as oxidative stress, inflammation, and DNA damage, are mostly influenced by
circadian rhythm genes.”

So, based on that and ongoing chronobiology studies, product usage synced to the body’s commands is scientifically sound and essential for the greater good. With no medication, just a few simple changes in your skincare routine will help skin do what it already wants to -- more efficiently.


Since skin is exposed to the sun’s ultraviolet rays, bacteria, and viruses, one of the skin’s primary functions during the day is to protect us from these potential dangers and ensure the next generation of new cells is unharmed.
What skin is facing:
- DNA Damage
- UV + Pollution = oxidative stress → photoaging and pigmentation
- Moisture Loss
- Skin Barrier Defenses under environmental siege

 

Day Skincare Routine, matched to the Circadian Cycle, using skin’s natural intelligence and SmartSkincare for protection and defense: sunscreen with DNA repair + antioxidants + hydrators.


1. Cleanse with RADIANT WASH, a Clarifying Gel with Buffered Fruit Acids dissolves dirt, dulling dead skin cells, excess oil and impurities for a smooth finish and restored radiance.
2. Prevent DNA damage with DNA TOTAL REPAIR, an intense Serum with 3 Pure DNA Repair Enzymes and super antioxidants corrects and repairs all visible signs of photodamage on contact.
3. Neutralize free-radicals with C 20+, an Antioxidant Serum packed with L-Ascorbic Acid, Vitamin E, Ferulic Acid, and AHAs confronts the origins of oxidative damage and the evidence of it all at once.
4. Moisturize with MULTI-ACTIVE DAY CREAM, a transformative antioxidant hydrator with Alpha-Beta-Retinol that limits oxidative damage and steps up skin microrelief with pronounced moisturizing.
5. Treat Eyes with ILLUMINATING EYE SERUM because delicate skin needs specialized care and DNA repair and this light-diffusing serum with cooling applicator acts instantly to de-puff.
6. Protect and Repair with SILC SHEER 2.0, a Broad-Spectrum SPF 40, micronized, oil-free, physical sunscreen with DNA repair enzymes, a mighty antioxidant and the cosmetic benefit of a skin-perfecting,
universal sheer tint.


At night, a remarkable change comes over the skin. Cells leap into action, dramatically ramping up DNA repair, protein production and cell division. This flurry of activity, signaled by circadian commands, is aimed at fixing the damage caused by the day’s environmental onslaught, such as UV rays and pollution, damage that leads to premature skin aging. The circadian system ties repair to the night hours when UV rays and other damaging influences are absent or minimized.


What science has proven: the circadian timeclock ramps up cell regeneration and DNA repair by least 30 times more rapidly at night than during the day.


What skin is putting in gear:
- Cell turnover and repair, peaking between 10 PM and 2 AM.
- Opening cellular pathways, allowing deeper absorption of active ingredients.
- Releasing melatonin and growth hormones to spark regeneration.
- Refilling hydration reservoirs


Night Skincare Routine, matched to the Circadian Cycle using skin’s natural intelligence and SmartSkincare for repair + restoration: DNA repair + exfoliation + ceramides + copper tri-peptide complex.


1. Cleanse with MICROFOLIANT CLEANSER, a perfectly pH-balanced exfoliating, pore-clearing, cell-refining gel formula with Alpha-Beta-Retinol dissolves surface cell buildup without stripping moisture levels.
2. Exfoliate with 5-SECOND DAILY PEEL, a one-step exfoliating treatment that helps to resurface the skin and promote cellular turnover. Formulated with a natural AHA 5-acid blend, beta hydroxy acid, and a superstar
form of vitamin A, 5-Second Daily Peel is individually packaged as a pre-dosed easy application.
3. Repair + Boost with ADVANCED HA, a self-correcting hyaluronic acid serum with DNA repair enzymes enables cell recuperation and forms a network to prevent cell degeneration and moisture loss.
4. Hydrate with NIGHT THERAPY, a fortifying and moisture recapturing complex with DNA Repair Enzymes +Copper Peptide Complex® uses the restorative hours of sleep to optimize renewal, elevate moisture retention
and inhibit the signs of free radical damage.
5. Repair + Nutrify with BODY REPAIR, a hyper-nutritive daily lotion supplies power DNA repair enzymes and Copper Peptide Complex, the antioxidant and anti-inflammatory compound that triggers cellular repair
immediately.

Trust Us: Night and Day Circadian SmartSkincare is not a whim. It’s a science-based approach that took
researchers years to unravel – a discovery, so significant it’s the future of skincare: sustainable, naturally
adaptive, transformational.