Creme de la Copper NEOVA
Creme de la Copper NEOVA
Creme de la Copper NEOVA
Creme de la Copper
 

Creme de la Copper

DNA Repair + Copper Peptide

1.7 fl. oz
$119.00

An intense patented moisturizing cream, with DNA CoFactor [DNA + Copper Peptide Complex], delivers powerful nourishing agents that help to organize mature skin into a dramatically improved moisture state and a stronger protective barrier.  Helps to retain elasticity and firmness and visibly smooth uneven skin tones. Recommended for all mature skin types.  Dermatologist tested.

Directions

Apply daily after cleansing and treatments.

Ingredients

Water (Aqua), Caprylic/Capric Triglyceride, Glyceryl Stearate, Propylene Glycol, Dimethicone, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Peg-100 Stearate, Palmitic Acid, Stearic Acid, Cetyl Alcohol, Polysorbate 20, Bis (Tripeptide-1) Copper Acetate, Arabidopsis Thaliana Extract, Lecithin, Vitis Vinifera(Grape) Seed Extract, Ceramide Eop, Ethylhexylglycerin, Hexylene Glycol, Allantoin, Ceramide Np, Ceramide Ap, Xanthan Gum, Sodium Lauroyl Lactylate, Glycerin, Magnesium Aluminum Silicate, Caprylyl Glycol, Aminomethyl Propanol, Glyceryl Behenate, Sodium Citrate, Sorbitan Sesquioleate, Polysorbate 60, Phytosphingosine, Cholesterol, Carbomer, Phenoxyethanol.

Regimen

Morning:

1. Cleanse with Radiant Wash

2. Apply Retinol Intensive Spray

3. Power Up with DNA Concentrate Activator

4. Treat with DNA Total Repair

5. Moisturize with Creme de la Copper

6. Protect with DNA Damage Control SilcSheer

Evening:

1. Cleanse with Radiant Wash

2. Apply Retinol Intensive Spray

3. Power Up with DNA Concentrate Activator

4. Treat with DNA Total Repair

5. Moisturize with Night Therapy

Clinical Studies

Skin Benefits of Copper Peptide Containing Facial Cream. A Study in the Role of GHK-Copper Peptides

  1. J. Leyden, M. D.a • G. Grove, Ph.D.b • T. J. Stephens, Ph.D.c • M.B. Finkey, M.S.d • S. Barkovic, B.A.d • Y. Appa, Ph.D.d

aUniversity of Pennsylvania Department of Dermatology, Philadelphia, PA • bKGL Inc. Skin Study Center, Broomall, PA • cThomas J. Stephens & Associates, Inc., Dallas, TX• dNeutrogena Corporation, Los Angeles, CA

The information presented in the article discusses DNA Repair Enzymes and their positive effects on photodamaged skin cells. It is provided for your information and education.

STUDY OBJECTIVE   To evaluate the ability of GHK-Cu containing face creams to deliver effective skin benefits.

STUDY DESIGN   GHK-Cu face creams were evaluated in two separate clinical studies

GHK-Cu Face cream vs. Retinol (0.075%) Benchmark

  • Eight-week double blind controlled study
  • 19 female subjects with mild to moderate photodamage

GHK-Cu Face cream vs. Placebo

  • Twelve-week double blind placebo controlled study
  • 67 female subjects with mild to moderate photodamage
  • Pinch recoil measurements in the crow’s feet area
  • Ballistometer measurement of skin firmness
  • Ultrasound measurement of skin thickness and density

STUDY SIGNIFICANCE   The benefits of tripeptide-copper complex containing preparations have been documented in the area of wound healing. At the time of the study, there were, however, no published studies in the area of facial skin benefits for them.

RESULTS & CONCLUSIONS    By week one, the test formula delivered significant

improvements in skin laxity, clarity, and overall appearance as compared to placebo. Significant improvement in fine lines was noted at week two and wrinkles at week eight over placebo. Significantly improved elasticity properties were consistent with ultrasound increases in overall skin density and thickness.

Subjects indicated strong acceptance of product performance and there were no adverse objective or subjective irritation findings. In summary, these studies demonstrate that GHK-Cu containing treatments rapidly deliver significant and sustained improvements in the appearance.

In a 12-week placebo controlled study1 of 67 subjects, the Copper Peptide Complex cream showed statistically significant changes in average clinical scores, indicating improvement in skin condition in week 12 when compared with placebo.

Indication

Week 4

Week 8

Week 12

Overall Appearance

28%

37%

43%

Laxity

20%

32%

39%

Clarity

58%

58%

59%

Fine Lines

28%

45%

53%

Mottled Hyperpigmentation

10%

15%

21%

Coarse Wrinkles

16%

43%

55%

 

Attribute

% of Improvement over Baseline

 

Wk 1

Wk 2

Wk 4

Wk 8

Wk12

Laxity

3%

8%*

19%*

32%*

39%*

Clarity

51%*

57%*

57%*

58%*

59%*

Mottled Hyperpigmentation

2%

3%

8%

15%*

21%*

Fine Lines

3%

10%

28%*

45%*

53%*

Coarse Wrinkles

1%

3%

16%

43%*

55%*

* Statistically Significant improvement

 

1Finkey,Mary Beth; Appa,Yohini;Bhandarkar,Sulochana,Copper Peptide

and Skin, Cosmetic Science and Technology Series,Volume 27, 549-564,

2005, Marcel Dekker, Inc.

 

 

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